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Biochemistry

BMI Weekly News - December 16, 2024

BMI Weekly Newsletter

December 16, 2024

News:

  • Two exciting new developments in BMI-connected science
  1. 2024 Science magazine Breakthrough of the Year

Work in the areas of virology, structural biology, antiviral compound development, and public health interventions has resulted in the development of lenacapavir, a new drug that can prevent HIV infections for at least 6-months after only a single injection.  The drug interacts with HIV capsid proteins in ways that prevent them from entering the nucleus to start new infections, as well as preventing capsids from leaving the nucleus during ongoing infections.  This drug has the potential to greatly reduce the ongoing impact of the HIV pandemic. https://www.science.org/content/article/breakthrough-2024  (attached as lencapavir.pdf).

  1. From the Darkness

In case there is a question about whether there will be anything useful left for young scientists to build long careers around, it turns out that human (and probably most other types) of genomes encode many more proteins than previously identified.  The “dark proteome” is the set of proteins expressed from short (or small) small open reading frames that are scattered around human, and likely other eukaryotic genomes.  Emerging evidence suggests that they will serve important biological functions. https://www.science.org/doi/epdf/10.1126/science.adu8277. (attached as DarkProteome.pdf)

  • Thank you to our BMI Social Activities Committee, Natalie Mcginnis and Lauren Pavelich, BMI Student President, Bhavita Bhaya, and to all the others that gave a helping hand and their support for our BMI holiday party celebration!

This Week’s Events:

  • No events scheduled for this week.

Upcoming Events:

  • The 28th Annual Chuan-Pu Lee Endowed Graduate Student Research Day will be on January 27, 2025.  REMINDER: Abstract submissions are now open and due this week, December 20, 2024. More information on this event and abstract submission can be found here: https://gsrpd9.wixsite.com/gsrpd
  • IFG Midwest Immunology Conference: The annual meeting of the Translational Research Cancer Centers Consortium (TRCCC) will be held February 19-21, 2025, Seven Springs Mountain Resort Champion, Seven Springs, PA. Host: Boris Pasche, MD, PhD, Director. Organizers: Wei-Zen Wei, PhD and Heather Gibson, PhD. The Barbara Ann Karmanos Cancer Institute. See the attached flyers for updates and event details.

Campus News:

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